“Regulation of tendon matrix and its mechanical properties in elderly individuals: influence of physical training”
The aim of the research is to improve our understanding of the mechanisms and potential of patellar tendon adaptation to resistance exercise in elderly individuals.
We perform US based in vivo testing of patellar tendon mechanical properties to determine changes in tendon stiffness before and after 3 or 12 months of resistance training of two different intensities.
Furthermore we take patellar tendon biopsies to analyse matrix protein content (collagen), collagen x-links (advanced glyction end-products) and tendon ultrastructure (with TEM).
Finally we perform MRi scans to analyse macroscopic tendon morphology (CSA).
The research will hopefully improve our knowledge about the benefits of training interventions to elderly and the biological mechanisms that serves to maintain healthy connective tissue in the ageing individual.
Prof. Michael Kjær and Prof. Peter Magnusson