The focus of our group is on the plasticity of skeletal muscle during cycles of damage and regeneration as well as during loss and gain of muscle mass under conditions of hospitalisation-induced bedrest and resistance training, particularly in elderly individuals. At the cellular level, we are interested in the response of the various muscle cell populations contributing to the adaptation response, which we study in vivo and in vitro. Pharmacological intervention in the form of non-steroidal anti-inflammatory medication or blocking Angiotensin II receptor signalling are currently being investigated in human studies.

Group members:
Abigail Mackey, Jesper Løvind Andersen, Peter Schjerling, Mette Heisterberg, Anders Karlsen and Cecilie J. Leidesdorff Bechshøft